Sentence examples for challenge largely from inspiring English sources

Future success of graphene-based applications hinges upon precise control of the graphene morphology over large areas, a significant challenge largely unexplored so far.

Determination of the molecular structures of GPCRs including chemokine receptor still remains an enormous challenge, largely due to the notorious difficulty to obtain large quantities of purified proteins.

Wall Street analysts say Firestone faces the biggest challenge, largely because the public has heard about recalled tires, not vehicles.

In Utah, Senator Robert F. Bennett is unexpectedly facing a strong intraparty challenge, largely because he sponsored a bipartisan health plan.

Annabelle Comyn's staging for Hatch Productions does not meet this challenge, largely because of undercasting: as Rosa and Eric, Ingrid Craigie and Conor Mullen do not move convincingly out of initial presentations of their characters as underwrought and emotionally deadened, and there is not much sense of the complicated emotional interdependence between them.

Determining when a slope will fail is a considerably more difficult challenge, largely due to the difficulty of observing or predicting the processes of material strength degradation.

Summary: Developing liquid chromatography tandem mass spectrometry (LC-MS/MS) analyses of (bio chemicals is both time consuming and challenging, largely because of the large number of LC and MS instrument parameters that need to be optimized.

Running simulation at large spatial scales however presents additional challenges, largely because reaction parameters in literature are mostly measured in relatively small scale laboratory systems at the spatial scale of 100 102 cm.

Only one beach, the relatively little-used Wolfe's Pond on Staten Island, received an undesirable rating of "challenged" — largely for the absence of signs warning beachgoers not to swim in areas without lifeguards.

A12 Fertility Clinic Rules Challenged Largely unregulated, fertility clinics have long operated under the assumption that preserving anonymity is best for all parties, but as the stigma of infertility fades both donors and recipients are attacking the secrecy of the process.

During the primary season, especially on the Democratic side, many pollsters missed their targets by a mile, for example by predicting that Mr Obama would win comfortably in New Hampshire, only for Hillary Clinton to triumph.This year has presented unusual challenges, largely because of Mr Obama.