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Since this line of interpretation seeks to downplay Locke's agnostic tendencies, one challenge is to account for Locke's pessimism about the possibility of our knowing real essences.
A related challenge is to account for Locke's appeals to superaddition, since prima facie, Locke's reason for invoking God is that he thinks the corpuscular hypothesis has no resources for explaining the four problematic phenomena.
If it's the former we let go of rather than the latter, then our challenge is to account for the fact that the choice is wrong despite the fact that that same choice seems to be good for – indeed maximizing for – each and every existing and future person.
Part of the challenge is to account for the relative contributions of both indoor and outdoor exposures.
This variation may include differences in rates of evolution, base frequencies, and substitution patterns, and the challenge is to account for all such variation found in any given dataset.
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Understanding motion perception continues to be the subject of much debate, a central challenge being to account for why the speeds and directions seen accord with neither the physical movements of objects nor their projected movements on the retina.
One of the first challenges was to account for unmet demand.
The challenge for (i) is to account for the difference in kind between the irrationality of common beliefs that are ungrounded and resistant to change (such as superstitious beliefs or beliefs in alien abductions) and the irrationality of delusions.
The central challenge facing such interpretations is to account for the passages in which Locke speaks as though he accepts the corpuscular hypothesis, most notably those in which he appears to identify the real essences of material substances with the corpuscles' primary qualities.
A key challenge for gyrification theory is to account for the factors that mediate cortical expansion to produce pattern-specific folding.
However, one of the fundamental challenges for synthetic biology is to account for the uncertain environment that the synthetic organism might eventually inhabit.
More suggestions(15)
challenge is to give
challenge is to relax
challenge is to remind
challenge is to stay
challenge is to reconcile
challenge is to get
challenge is to procure
challenge is to draw
challenge is to engage
challenge is to put
challenge is to keep
challenge is to sneak
challenge is to preserve
challenge is to add
challenge is to spread
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CEO of Professional Science Editing for Scientists @ prosciediting.com