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The additional experience gained since the Act was passed indicates that the magnitude of that challenge has increased as progress is not being made at a rate necessary to hit the targets.
This challenge has increased as high-throughput sequencing technologies increase the size of datasets.
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By 2012 the complexity and subtle nature of the challenge had increased, the challenge now being an understanding [17] of how asymmetric induction in the resulting polymer can be achieved.
This suggests that coelomocytes responding to an immune challenge have increased gene expression that requires a coordinated increase in the expression of proteins involved in RNA splicing and processing.
But legal challenges have increased, and some critics refer to a court decision last year in San Diego as a possible turning point in the use of cameras.
Along with this, the ethical, boundary, and systemic challenges have increased, heightening the need for development and evaluation of robust clinical supervision methods [ 29].
The plan also demonstrates how the BBC will continue to reinvent public service broadcasting for a new generation - a challenge which has increased in both importance and urgency amid a fast-changing media landscape.
To meet this challenge, the UC Berkeley School of Public Health has increased its commitment to the field of aging, including the development of special courses, field placements, and research opportunities.
The importance of city governance to tackle the challenges of biodiversity loss has increased as urban population has grown enormously in the last decades, particularly in developing countries.
Hostage-taking has increased, challenging the new Iraqi government and reflecting an intensifying campaign against citizens whose countries provide troops or subcontracting work for the American-led military presence.
Although our understanding of the factors that influence the safety and efficacy of these therapies has increased, challenges for bringing genetically modified T-cell immunotherapy to many patients with different tumour types remain.
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