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Thus, intra-tumor heterogeneity poses a tremendous challenge for the characterization of biomarkers and treatment selection.
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Future challenges for the characterization of tumors based upon phosphorylation signatures include the relative sparseness of data (especially among multiple samples), the convolution of protein levels with phosphorylation levels, and the semi-quantitative nature of spectral counting for measuring peptide abundance.
The presence of hundreds of copies of mitochondrial DNA (mtDNA) in each human cell poses a challenge for the complete characterization of mtDNA genomes by conventional sequencing technologies.
A central challenge for the molecular characterization of cell-wall biopolymers involves focusing on the material of interest without compromising its inherent molecular structure.
Therefore, the in present investigates a potential bacterial strain was isolated and screened from pulp and paper mill sludge and examined its ability to decolorize/degrade lignin, which is a major challenge for the pulping industry and characterization of its metabolic products.
One remaining challenge is the characterization of the structure of the hydrated polymer shell.
So even if the notion is understood well enough for some objects (never mind that not everyone would allow that the number 2, for example, is an object), a major challenge for the advocate of the definitional characterization is to provide a respectable general understanding of the notion of a definition for an object.
When a reporter describes Mr. Sims as angry in a public debate, he will challenge the characterization.
A key challenge is doing this while maintaining sufficient sensitivity for the characterization of these compounds.
However, the dynamic nature poses a great challenge for characterization because structure and property depend on the external conditions.
Despite its sensitivity and versatility, LSPR as a label-free method for the characterization of biomolecular interactions faces the challenge of distinguishing nonspecific binding in its measurements.
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