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From there, the challenge escalates as the Endurance is crushed and sunk, and the men are left to slog across great stretches of ice pack and row tiny open lifeboats for days through treacherous currents that wouldn't let them beach their craft once land was reached.
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Challenges escalated, but we kept going and he finished his work on the manuscript.
Contract law and private property are under increasing attack, with constitutional challenges escalating and providing a last bulwark against the morass of federal overreach.
Shatzkin's take is that "what brick-and-mortar booksellers will experience in the first six months of 2011 will be the most difficult time they've ever seen, with challenges escalating beyond what most of them are now imagining or budgeting for".
The challenge has escalated.
Mr. Trump's tendency to lash out when challenged further escalates the possibility of disputes spinning dangerously out of control.
No matter who wins in November, it's clear that solving challenges like escalating health care and energy costs will require close cooperation between corporate leaders and Washington.
It is struggling to ensure health care for the poor while not bankrupting the state -- all of this within a health care system challenged with escalating costs, increasingly dissatisfied consumers and providers, and one of the lowest life expectancies in the developed world.
The pharmaceutical industry, particularly the small molecule domain, faces unprecedented challenges of escalating costs, high attrition as well as increasing competitive pressure from other companies and from new treatment modes such as biological products.
Regulated by a mysterious trio known only as Game Soc, the challenges quickly escalate from innocuous pranks to personal embarrassments that soon cause the friends to turn on each other.
Complex scientific challenges, including escalating global climate change, overpopulation, environmental degradation, and the emergence of new pathogens, demand new types of scientific responses (American Association for the Advancement of Science [AAAS], 2009).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com