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The biggest challenge at present, Ono says, is contaminated water.
Modeling the hydraulic fracture propagation is still a challenge at present because of the constantly moving boundaries and coupling effects among solid and fluid (Wang 2015).
Inditex's biggest challenge at present is to keep up with online-only fashion websites, including Germany's Zalando and the UK's Asos.
However, the acquisition of efficient Z-scheme visible-light photocatalysts is still a huge challenge at present due to the inactive visible light-active component and various low-band-gap for semiconductors.
Predicting the scope and impact of further protests (and crime) on thousands of tourists, many of them uninformed, is certainly a challenge at present -- but we know it could be significantly disruptive.
Finally, addressing the issue of equity in maternal health care, that continues to pose a formidable challenge at present, may hold the key for the achievement of Millennium Development Goals for India in the near future.
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Nanoelectrodes using CNTs, graphene and CNFs have been reported to meet these challenges at present.
However, a practical control of vortex chirality is rather challenging at present stage, not to mention via mechanical methods.
Polymer electrolyte membrane (PEM) with high loading, stable ion solvents remains challenging at present and significantly impedes its practical application in energy-relevant devices including hydrogen fuel cell.
Designing PBRs for photocatalysis is still challenging at present, and most reactors are designed and scaled up using semi-empirical approaches.
Although such markers have been incorporated into recent diagnostic criteria for Alzheimer's disease, 25 26 whether they are effective at predicting those who will develop dementia 29 and, more importantly, practically acceptable, makes their widespread clinical use challenging at present.
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