Sentence examples for chains of residues from inspiring English sources

They are defined at the level of a single molecule while biomolecules are described by chains of residues.

Many of them are formed by side chains of residues of Lq2 and backbone atoms of the K+ channel.

Thus, for reasonably efficient catalysis, PRK requires anionic character in the side chains of residues 42 and 169.

Many of them are formed by side chains of residues of MTX and backbone atoms of the Kv1.2 channel.

After helix III has docked, it adopts an α-helical secondary structure, and the side chains of residues within this region provide contacts that are crucial to native-state stability.

In the two crystal structures, the final refined structural models contained the intact peptide chains of residues 10 400 and 14 400, respectively, and were both in the inward-facing conformation consistent with the previously reported Dxc-ecMdfA structure (Heng et al. 2015).

The crystal structure of PfdUTPase in complex with one of these inhibitors suggested that the triphenylmethane derivative was selective due to a series of interactions between the trityl group and the side chains of residues Phe46, Ile117 and Lys96 located in a hydrophobic pocket distinct from the phosphate binding site.

Additional smaller changes in the side chains of residues 151, 70, and 72 were also observed (Fig. 5).

Thus, a close structural similarity, particularly a characteristic orientation of the side-chains of residues Lys606, Leu607 and Ile608 in the loop, was found in certain β3-analogues that were better recognised than the parent peptide by anti-peptide mouse monoclonal antibodies and patients' antibodies.

We and others have previously shown that the side-chains of residues 72 and 65 interact with each other [35] and with Q151 and the α- and γ-phosphates of the incoming dNTP [26] or TFV-DP [45].

Several different models of the gp41 MSD have been proposed: the 'classic' model with a 25 residue MSD (683 707 HXB2 numbering) and a 'snorkeling' model with a 12 residue core between 683 696 (HXB2 numbering) which exposes the charged side-chains of residues K683 and R696 to the polar head groups of the lipid bilayer [53], [59].