Sentence examples for chain terminator from inspiring English sources

Exact(41)

Although a number of studies have reported on chain termination events, the actual chain terminator and termination site in the biological systems remain unknown.

The detection of [H]-sT-CH2-CoA and [H]-sD-CO2H not only highlight the importance of penultimate HB unit in PHB chain but may also shed light on the possible termination site and chain terminator in vivo.

C-tails were added to the sheared DNA using the terminal transferase kit (New England Biolabs, MA) and the chain terminator ddCTP (GE Healthcare Biosciences, NJ).

The M250V substituted HBV RT in the absence of LVDr changes was constructed and tested for susceptibility to LVD, an obligate chain terminator which should not be impacted by the mechanism that could potentially affect ETV chain termination.

Graziewicz, M.A. et al. Fapyadenine is a moderately efficient chain terminator for prokaryotic DNA polymerases.

This nucleoside KP-12122) is not a chain terminator but exerts its antiviral effects via mutagenesis of the viral genome.

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Similar(19)

N-Blocked phosphoranimines were prepared and used as chain terminators to control the molecular weights of these polymers.

We showed that their diphosphate forms S-PMEApp 5 and S-PMPApp 6 are readily incorporated by wild-type (WT) HIV-1 RT into DNA and act as DNA chain terminators.

Single-sided primer extension with dideoxynucleotide chain terminators is avoided, with the consequence that the sequencing fragments are derived directly from the original PCR products.

Sanger method of DNA sequencing used ddNTPs as the chain terminators in addition to usual dNTPs in the ratio of 1 100 to sequence the phage ϕX-174 DNA (5,386 nucleotides) using polyacrylamide gel analysis (Sanger et al., 1977).

Nucleoside analogues (NAs) can either act as chain terminators after being incorporated into growing DNA/RNA strands and/or inhibit the viral polymerase function by competition with the natural nucleoside 50-triphosphate substrate [3].

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