Sentence examples for chain modification from inspiring English sources

The C-24 oxidation pathway, the main side chain modification pathway is initiated by hydroxylation at C-24 of the side chain and leads to the formation of the end product, calcitroic acid.

To impart functionality as early as possible in the starch production chain, modification can be achieved directly as part of the developing starch storage roots, tubers, and seeds and grains of the crop.

The effects of side chain modification and chirality in linezolid-like 1,2,4-oxadiazoles have been studied to design new potent antibacterials against Gram-positive multidrug-resistant pathogens.

The analog JKF was designed to separate its calcemic activity from other biological activities by combining a calcemic-lowering 1-hydroxymethyl group with a potentiating C, D-ring side chain modification including 24 difluoronation.

The C-23 and C-26 oxidation pathways, the minor side chain modification pathways are initiated by hydroxylations at C-23 and C-26 of the side chain and lead to the formation of the end product, calcitriol lactone.

The C-4 side chain modification of lead compound 1 has resulted in the identification of a potent and selective Candida albicans N-myristoyltransferase (CaNmt) inhibitor RO-09-4609, which exhibits antifungal activity against C. albicans in vitro.

Additional side chain modifications resulted in the introduction of hydrogen bond interactions.

This results in the arrest of the C-24 hydroxylation initiated cascade of side chain modifications at the C-24 oxo stage, thus producing the stable C-24 oxo metabolites which are as active as their parent analogs.

Metabolic engineering at the level of side chain modifications may allow specific alterations of glucosinolate profiles, which may facilitate further investigations of the physiological and ecological role of glucosinolates.

Two other amino acid side chain modifications show a similar selectivity for single proteins.

Assignment of each pick was consistent with an alkane structure back bone bearing several side chain modifications (Figure 3a).