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If the UniProt record has no chain feature or more than one chain feature, start-end coordinates are added to every EWAS derived from it.
The UniProt record has more than one or no Chain feature.
Differently, "attached edge" and "chain feature" rely on the dependency tree and graph information, especially the SDP.
Finally, there is a sixth "chain feature" class, which focuses on the information of the whole SDP instead.
Combinations of features for trigger detection show that the "content feature" in trigger detection is the most important one, and the "chain feature" is the worst.
If the start and end coordinates of the EWAS agree with those of the Chain feature, the coordinates are deemed unnecessary and not added to the gene symbol.
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CEO of Professional Science Editing for Scientists @ prosciediting.com