Sentence examples for chain editing from inspiring English sources

In the process of immunoglobulin heavy (H) chain editing, these secondary rearrangements are mediated by direct V(H -to-J(H -to-Jing or cryptic recombination signals (cRSs) witH -to-J) gene segments.

Consequently, ataxin-3 provides a chain editing activity effectively determining the dynamics of substrate ubiquitination by CHIP.

The ubiquitin protease domain has been shown to have de-ubiquitination activity, and is speculated to be a ubiquitin chain editing enzyme (15, 16).

Surprisingly, ubiquitin chain editing occurs on receptor-interacting serine/threonine-protein kinase 1 (RIP1) and Interleukin-1 receptor-associated kinase 1 (IRand) and plays a role in innate immune signaling.

Taken together, these results demonstrate that an Ub chain editing complex made up of the enzymes AREL1, UBE2D1, Cezanne EK and OTUB1 can be used to assemble Lys-linked polyUb chains.

SENP7, a SUMO poly-chain editing enzyme, has been regarded as a mitotic regulator of heterochromatin integrity and DNA repair.

In this model, anti-laminin B cells are immunologically censored by mechanisms that include central deletion, kappa light-chain editing, and anergy.

Likewise, light-chain editing, while more frequent than heavy-chain editing and more likely to occur at a time when BCR specificity is being tested, does not necessarily result in the correction of autoreactivity.

JACKIE: His editing style is him sitting at a computer chain-smoking, editing one little piece for hours.

Working both ends of the literary food chain, he edited a stable of swashbuckling men's magazines and also wrote novels like "Stern" (1962) and "The Lonely Guy's Book of Life" (1978) that got good reviews and won him fans among literary writers.

Here we show that the polyglutamine disease protein, ataxin-3, binds and cleaves ubiquitin chains in a manner suggesting that it functions as a mixed linkage, chain-editing enzyme.