Our data, thus, provide support for model A, although some use of short chains cannot be excluded, as the enzymes involved are in principle capable of transferring poly-ubiquitin units.
Therefore, a nearly constant anion coverage in the entire Ag UPD range cannot be excluded.
Depending on the orientation of the positively charged side chains, it cannot be excluded that the charge density prevents strand pairing in the Tet1 CXXC domain.
Even though a steric effect (i.e., an effect on the volume of the pocket) imposed by the side chain of Val86 cannot be excluded, the results of the present analysis argue against a significant role of residue 86 on the choice of peptide residue accommodated by pocket P1.
Especially, the accumulation in terrestrial organisms, as shown for long-chain PFAAs [70], cannot be excluded [71].
However, consumption of long-chain n-3 PUFAs cannot be excluded in this group either, because women with isolated respiratory allergy had the highest intake of fatty fish of all groups.
The ECD fragmentation pattern suggests that the phosphoramidate group is located mainly on the lysine side chain, although a partial phosphorylation of the N-terminal amino group cannot be excluded.
There is insufficient data on the toxic properties of short-chain PFAAs [66], and therefore, sub-lethal long-term effects cannot be excluded.
However, it cannot be excluded that these cells also express endogenous TCR chains and hence may have encountered TCR agonist ligands intrathymically.
Nevertheless it cannot be excluded that in addition to the polar head group the hydrocarbon chain or a part of it contributes to the binding region.
