Sentence examples for cetp from inspiring English sources

Another key drug target is an enzyme called cholesteryl ester transfer protein (CETP), which affects levels of "good" cholesterol, that help protect against heart disease.

In 2004, an early study of people taking that Pfizer drug, a CETP inhibitor called torcetrapib, reported that it could lower bad cholesterol and improve good cholesterol.

Anacetrapib works by inhibiting an enzyme called CETP, which is involved in transforming particles of good cholesterol into bad cholesterol.

Scientists said that they left the door at least slightly open to similar drugs in development from Merck and Roche, which are called CETP inhibitors.

But over all, Dr. Rader wrote, "it is premature to announce the death of CETP inhibitors on the basis of the torcetrapib experience alone".

Merck and Roche have not disclosed whether they intend to begin large Phase 3 trials for their CETP inhibitors.

Dr. Nir Barzilai of the Albert Einstein College of Medicine has found that lucid Ashkenazi Jewish centenarians are three times more likely to carry a gene called CETP, which appears to increase the size and amount of so-called good cholesterol particles, than peers who succumbed to dementia.

Dr. Michael Davidson, clinical professor and director of preventative cardiology at the University of Chicago, said that because of torcetrapib's failure, the Food and Drug Administration would not approve any CETP inhibitor until it had been tested in large trials to prove it reduces the risk of death and heart attacks.

"I think we're going to see cautious development of CETP inhibitors," said Dr. B. Greg Brown, professor of medicine and cardiology at the University of Washington, who has consulted for all the companies.