At a cost of $1,400 per quitter, smoking cessation was cost-saving when caregiver costs were included, and cost about $200 per QALY gained when caregiver costs were excluded.
The first-line maintenance erlotinib therapy cost (modeled for time to treatment cessation), medication cost in later lines, and cost for the treatment of adverse events were included.
Probabilistic sensitivity analysis was performed to examine the combined effect of the uncertainty in all the variable parameters (survival, treatment cessation, unit cost, use of resources, etc).. Values were sampled from the uncertainty distributions associated with each parameter.
Compared with unaided cessation, varenicline cost was €320 per QALY gained.
One observational study conducted by Pollack 47 found that a cessation intervention costing US$45 per person would avert 108 SIDs if given to all pregnant smokers in the US, suggesting that the cessation service would cost US$2105000 per SID averted.
Our model predicted that smoking cessation was cost-effective even when only its impact on macular degeneration and mortality were considered.
This indicates that our finding that smoking cessation is cost-effective in terms of its impact on macular degeneration alone is also robust to plausible variation in the cost per quitter, and can be generalized to most, if not all, tobacco control strategies.
20 23 A systematic review including three trials examining the benefit of covering the cost of smoking cessation treatment (primarily the cost of pharmacotherapy) found that cost-free treatment increased the odds of achieving abstinence (OR 1.6; 95% CI 1.2 to 2.2) compared to having smokers pay for their own treatment.
"These advantages suggest that e-cigarettes have the potential to increase rates of smoking cessation and reduce costs to quitters and to health services".
For all OPV cessation options the costs drop dramatically after OPV13 cessation in 2019, which coincides with the cessation of SIAs for RC without SIAs.
