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This uncertainty could be reduced by conducting experiments to measure or constrain parameter estimates, which may lead to a more focused set of expectations from the trial due to greater certainty of the underlying biology and its connection to disease.
More elaborate expert judgment of overall uncertainties is presented in the full report (Hänninen and Knol 2011), where the statistical uncertainty of the exposure response functions is combined with the estimated level of certainty of the underlying knowledge on causality.
Similar(58)
Once the diagnosis has been defined with certainty, secondary forms of TCH must be managed through treatment of the underlying brain disorder.
Again, treatment is of the underlying disorder.
Treatment is of the underlying disorder.
Monitor the color of the underlying skin.
A cause of death evaluation process was designed to ensure a uniform and unbiased determination of the graduation of certainty that lung cancer was the underlying cause of death.
The clinical diagnosis of TES is not meant to imply a certainty of underlying CTE neuropathological changes (for example, p-tau accumulation).
One of the features of the DSPR is that the underlying mosaic haplotype structure of every RIL is known with a high degree of certainty via an HMM (King et al. 2012b).
Of more relevance are the underlying dynamics.
Although the underlying cause of fibromyalgia is not known with certainty, there is evidence that fibromyalgia runs in families.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com