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Model constraints during simulations were set by either experimental data collected as part of this study (Additional File 1) or, if certain uptake rates or other experimental data were not available, by setting the lower bound to the initial concentration of that particular compound in the experimental BCS growth medium [ 24].
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This preference was directly correlated with the expression of certain nitrogen uptake and assimilation systems in the root.
When NCC and SSD were used, this was applied to images before registration to create temporary images that were used as input for the image registration, thereby increasing proper matching of certain high uptake regions that can vary highly amongst different scans, i.e. the bladder.
The constraints of certain metabolite uptake rates were obtained from the literature [ 38, 39].
Since it is impossible to be entirely certain what uptake might be attained for any screening test in any population, base-case values were chosen to be conservative.
The simulations of succinate dehydrogenase deficiency were very similar to fumarase deficiency in both the reduction in ATP production and the effect of increasing certain metabolite uptake rates.
Rice plants uptake certain amount of Fe, but the plant may not translocate it to endosperm positively.
The results indicated that most of CdS were retained by the lungs after injection intravenously to mice, and the tissues of the liver, spleen, and kidney had also a certain degree of uptake; the largest accumulation were got at 6 h for the heart, liver, lungs, and kidney tissues (Fig. 5).
In some organisms, such as Drosophila, certain cells efficiently uptake dsRNA but seem to be unable to transmit this dsRNA to other cells in the fly body [ 24].
Despite these flaws, qualitative studies covered context-specific social scenarios offering explanations for why certain factors influence uptake from the perspectives of users.
Whilst there remain challenges in building a sufficiently robust evidence-base on which to devise screening policy [ 9], further research questions continue to be posed, including whether sustaining a certain level of uptake with repeat systematic screening could lead to a reduction in chlamydia prevalence [ 7].
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