Sentence examples for certain replication from inspiring English sources

Thus, Mcl1 might regulate the recruitment of a HDAC to the kinetochore domain in certain replication foci, though fission yeast centromeres are known to be replicated early in S-phase.

Furthermore, certain replication timing changes can directly lead to overt genomic instability and may explain unique mutational signatures that are present in cells that have undergone the recently described processes of "chromothripsis" and "kataegis".

In this paper, we will extend the BPPC to ensure that a certain replication factor m for each fragment of the relational table is obeyed; that is, for each fragment stored at one server there are at least m - 1 other servers storing a copy of this fragment, too.

It has been previously determined that certain replication errors are influenced by flanking regions adjacent to the mutation site.

In certain replication studies [ 106], the number of participants was too small and the functional relevance of the identified polymorphisms remains unclear.

As evident from this table, partial homologues to certain replication origins exist in some genomes, occasionally in addition to their complete homologues.

Two examples are staufen-1 (STAU1) mediated decay (SMD) and the decay of certain replication-dependent histone mRNAs at the end of S-phase of the mammalian cell cycle [ 27- 29].

Previously, we and others demonstrated that infection with certain replication-defective (apoptotic) HSV-1 viruses, such as those deleted for the regulatory ICP4 [ 19] or ICP27 [ 33] proteins, induce apoptosis in infected cells.

More recently we showed that archaeo-eukaryotic type primases (and prim-pol proteins with both primase and DNA polymerase activity) also contain a derived version of this fold, which is further related to DNA-binding domains of certain viral replication initiation proteins and the catalytic domain of rolling circle replicator tyrosine recombinases [ 5].

During replication, certain mutations push these systems out of control as to give a resistant phenotype to the mutants.

But under certain conditions, cell replication can occur before the DNA damage is repaired, resulting in the formation of mutations.