Our analysis of Sec7 deficient D. discoideum cells revealed that loss of the protein affected several cellular processes including altered secretion, growth under certain conditions, phagocytosis, cell motility and phototaxis (Table 6).
The finding that BCL2 expression can inhibit motility of certain cell lines suggests that there may be a reduced potential of these cells to metastasize and may help explain why there is a higher survival rate in patients with certain tumor types that overexpress BCL2 53.
Furthermore, we showed that elevating c-di-GMP levels up to a certain threshold inhibited the swimming motility of B. amyloliquefaciens PG12.
We, too, were rather surprised by the effects of certain NL insertions on kinesin motility.
More and more studies are finding that certain factors which affect swarming motility also influence other bacterial multicellular behaviors, especially biofilm formation (Harshey 2003; Verstraeten et al. 2008).
In particular, H. pylori mutants that do not express the CagL protein are unable to stimulate cell migration, while H. pylori strains that are deficient for CagA still activate motility to a certain extent [ 23].
The identified indels and SNPs in 'PCC-M' are likely to affect glucose tolerance, motility, phage resistance, certain stress responses as well as functions in the primary metabolism, potentially relevant for the synthesis of alkanes.
The role of reduced fiber and fluid intake and decreased physical activity is questionable, whereas underlying health problems more prevalent with advanced age (eg, diabetes mellitus, PD, dementia) and the use of medications (ie, calcium supplements, opioids, certain antidepressants) potentially affecting gastrointestinal motility and evacuation of stools are often involved (Table 1).
A threshold in semen motion pattern, i.e. non-linearity in sperm movement above a certain value, could help to detect abnormal semen motility and could subsequently stimulate an investigation into PRRSV infection.
Features such as motility, as well as certain biochemical properties, including the ability to synthesize an enzyme known as ornithine decarboxylase, are used to distinguish Enterobacter from the very similar and closely related Klebsiella bacteria.
