A certain machinery quietly goes into gear.
Guards, for instance, can open only some doors, while lab technicians have special skills needed to operate certain machinery.
At one candy company, certain machinery was washed only once a year, though it was used for chocolates with and without peanuts.
Signaling [12] and membrane [38] compartmentalization during cell migration and the ability of cells to respond rapidly to directional cues point to the possible existence of innate mechanisms to compartmentalize certain machinery necessary for the migration and polarization [11].
Liu et al. showed that gp78 can indeed tag certain machinery proteins with ubiquitin, which would stop the removal of misfolded proteins from the endoplasmic reticulum.
Therefore, we believe that the transgene silencing was caused by certain silencing machineries and not due to the loss of proviral DNA.
Metals present in environment render the bacteria to attain certain resistance machinery to survive, one of which is transformation of metal ions to nano forms.
Alternatively, the immune system may be programmed to develop anti-inflammatory and/or regulatory responses to microbial stimuli as a default setting, unless certain specialized machinery such as toll-like receptors provide the additional signature indicating the stimuli are derived from specific dangerous pathogens.
Do leukocytes prearrange certain molecules and machineries in a polarized fashion prior to the acquisition of polarized morphologies, or are extrinsic cues alone responsible to induce all events required for cellular polarization?
Conversely, the RNA interference (RNAi) and exosome machineries, certain HATs and an active RNA polymerase II (Pol II) have been documented to contribute directly to the assembly of heterochromatin (Volpe et al., 2002; Djupedal et al., 2005; Kato et al., 2005; Buhler et al., 2007; Xhemalce and Kouzarides, 2010; Reyes-Turcu et al., 2011; Yamanaka et al., 2013).
