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The expression of the let-7 family detected in the middle of the pregnancy suggests a certain level of negative regulation of cell growth in the 27-week fetal liver.
Surprisingly, although by day 10 and 17 we were able to observe a certain level of restoration of T cell stimulation, it never achieved the levels of the controls (Fig. 5A).
Like in every complex system, there is a certain level of stochasticity and uncontrolled cell proliferation can take over.
Above a certain level of phosgene, damage to cells will result in cytotoxicity, i.e. cell death.
Another hypothesis might be that above a certain level of replicating mycobacteria, T-cell responses are not detectable in vitro as T-cells might be exhausted or sequestered at the site of infection.
We found effector T cells derived from central memory T cells improved cell viability, maintained certain level of CD62L expression, and reacquired the CD62L+CD44high phenotype of central memory T cells after effector T cells differentiation.
As a consequence, normal cells can tolerate a certain level of exogenous ROS whereas cancer cells cannot.
Tissue homeostasis requires a certain level of phenotypic plasticity from resident cells and also the involvement of circulating cells.
This reveals that the ancestral cells show a certain level of coherence and do not mix freely with the other cells of the embryo before their allocation to the SE.
Biologically, it has been known that there is certain level of overlap between transit amplifying (fast dividing) cells and lineage committed cells in the intestine.
However, the experience has shown that most of the time, a certain level of signal is received from several cells simultaneously (it does not mean the quality of the signal is appropriate to attempt a call) or cellular technologies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com