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Another report in Science led by Jesse Silverberg of Cornell University altered the stiffness of an origami-folded surface simply by pushing out certain folds and introducing reversible defects.
Does the ability to bridge them relate to the observation that certain folds, such as TIM barrels, accommodate numerous functions, whereas other folds support only one?
Recently reported ancestral elements, like the α/β class and certain folds, were remarkably found to act as hubs in the networks.
The recurrence of certain folds, such as the TIM-barrel, the Rossmann-fold or the alpha/beta hydrolase domain, in the sets of NISE reflects the biochemical versatility of these domains because of which they are, in a sense, "pre-adapted" for evolution of NISE.
Sometimes it can be difficult to figure out certain folds but if you are patient you will eventually figure it out.
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DnaK prevents off-pathway reactions or stabilises certain folding intermediates.
Seroconversion is defined as a certain fold increase in specific antibody titres before and after vaccination, e.g. at least a fourfold rise in the case of influenza vaccines.
In other words, sequences corresponding to a certain fold are greatly confluent: the same structure corresponds to somewhat dissimilar or even totally dissimilar sequences.
For example, in the case of the P. sojae V1.0 assembly, one can query and find all the transcripts that show a certain fold change (e.g. two-fold) between infection and non-infection conditions.
The linear correlation between the Ct values (threshold values) and the initial cDNA amounts, diluted to a certain fold, confirms the accuracy of the method within a wide working range.
We partitioned the genes that were induced by this treatment into distinct kinetic clusters according to their response time (i.e., according to the first time point in which a gene was induced above a certain fold-change threshold).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com