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The number of inducing substances need not, however, be the same as the number of different kinds of tissues and organs, since certain differentiations could possibly be induced by a combination of two or more inducing substances, or the same inducing substance might have different effects on different tissues.
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Proliferation and differentiation are incompatible: promoting cell proliferation diverts the cells from differentiating and consequently, certain differentiation markers are suppressed by EGF.
The findings of this study inform lecturers on how they should prepare lessons to guide students to understand and apply restrictions of certain differentiation rules and formulae.
This study suggests that teaching of the standard rules of differentiation should put emphasis on its restrictions to eliminate common errors that normally crop up due to over-generalisation of certain differentiation rules.
THP-1 cells express CD206 in certain differentiation protocols [38].
First and foremost, factors steering cells along certain differentiation paths are expensive.
The present modeling concept assumes that state-specific noise regulation in response to environmental signals serves as a selector of certain differentiation states representing specific functional cellular programs.
Cardinal features of these stem-like cells are long-term self-renewal, tumorigenicity upon xenotransplantation to immunocompromised mice, and a certain differentiation capacity.
We found that certain differentiation markers (i.e., Krt3 and CX43) were not found in the normal limbal basal epithelium or central corneal epithelium of CUCC patients; rather, these markers were only detected in the central corneal epithelium but not the limbal basal epithelium of a normal cornea.
Hypoxic conditions induce the transcription factor hypoxia-inducing factor-α which can promote certain differentiation phenotypes in MSC.
The switch in certain differentiation markers is accompanied by functional changes required for cells to migrate and invade the ECM.
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