Assuming that certain technical challenges regarding the manufacturing of regulatory T cells can be overcome, a wide variety of clinical applications can be envisioned using adoptively transferred CD4+CD25+ regulatory T cells.
There are, however, certain methodological challenges regarding choice of treatment and control groups.
They are facing two key challenges regarding hard data.
There have been several failed Supreme Court challenges regarding the practice.
There are several challenges regarding tumour measurements.
At the same time that attention is being paid to the role of CHWs, certain challenges have emerged regarding their performance.
This presents certain challenges with regard to heritage management, since their extents are largely unknown, normally only being identified when exposed by wind and storm erosion.
The acquisition increased the challenge regarding employee freedom.
This year, the EBU has an extra challenge regarding Eurovision.
"There were certain challenges.
