Sentence examples for certain cascade from inspiring English sources

Given high mutation rates of genes in cancer cells, it is likely that, even if we block a certain cascade with a targeted drug, there will be at least a sub-population of cells in a tumor which could circumvent such a block by using an alternative signaling route.

"There is a certain biological cascade where smoking is involved," Dr. Kurth said.

The idea was that you needed to keep your eyes looking ahead, arms out in front and that looking down was a certain ignominious cascade to the pavement and sure embarrassment.

For example, one may predict that certain signal cascade architectures dissipate information more strongly and lead to double logarithmic scaling and loss of sensitivity at certain input levels.

Although phosphatase levels modulating certain kinase cascades have been suggested to be too large for signal penetration into the nucleus, our results may be applicable to kinase cascades over shorter length scales or to other cascaded signaling modules.

Physically interacting proteins in signaling networks often form protein complexes that are used for isolating certain signaling cascades from other reactions, or signaling protein translocations.

Physically interacting proteins in signaling networks often form protein complexes that are used for isolating certain signaling cascades from other reactions, or for signaling protein translocations.

Activated arrestin-bound complexes can desensitize certain signalling cascades, such as those mediated through Gα, and also propagate distinct signalling processes through scaffolding various precursors to pathways resulting in MAPK, c-Src and Akt activation (DeWire et al., 2007).

These two stereoisomers have different biophysical properties in membranes and previous work has shown that the sn-1,2 stereoisomer is much more potent, compared to sn-1,3-DAG, at activating certain signaling cascades linked to insulin resistance [ 4].

Of particular interest, however, was our observation that certain signalling cascades, including those mediated by Igf1 and Vegf, were differentially activated by cluster 1 and cluster 2 K-Ras mutants, suggesting that not only the presence but the specific molecular characteristics of individual K-Ras mutations may be important determinants of both tumour progression and treatment response.

Under a suitable condition on the zero-dynamics with time-delay, we prove that global state regulation can be achieved by a partial state adaptive controller for certain time-delay cascade systems with unknown parameters.