Findings of cerebrospinal fluid analysis, including levels of lactic dehydrogenase isoenzymes, were compared with an age-matched reference group.
In two patients with meningitis, lumbar puncture with cerebrospinal fluid analysis was repeated because of inadequate response to treatment or initially obscure etiologic pathogens.
Two biomarkers are used to indicate dementia: deposits of beta-amyloid in the brain, as seen with positron-emission tomography (PET) scans, followed by degeneration of brain neurons (neurodegeneration), found through cerebrospinal fluid analysis (spinal tap).
L. donovani (LD) was detected by polymerase chain reaction (PCR) on cerebrospinal fluid analysis.
Although the results of a cerebrospinal fluid analysis were normal, treatment with acyclovir was initiated.
An expansion of routine investigations should be performed in cases where the neurological examination, cerebrospinal fluid analysis, and computer tomography are normal.
As no cerebrospinal fluid analysis could be performed in the present case, the patient received treatment for neurosyphilis despite the absence of retinal/optic nerve involvement, with the subsequent resolution of intraocular inflammation and healing of the tongue chancre.
The cerebrospinal fluid analysis revealed less pleocytosis (18 versus 1330 white cells per mm3, p < 0.001), less polymorphonuclear neutrophils (55 vs. 90%%, p < 0.001), higher glucose level (4.1 vs 0.8 mmol/L, p < 0.001) and lower protein level (482 vs 1608 mg/L, p < 0.001) in the CNS group.
After a complete physical examination and an extensive diagnostic work-up that included a visit to a veterinary neurologist for a MRI and cerebrospinal fluid analysis, I concluded that Samurai was suffering from CDV.
