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This open-label, single centre pilot study was designed to evaluate safety and tolerability of the combination of the drugs isosorbide dinitrate, a nitric oxide donor, and ibuprofen, a non steroid anti-inflammatory drug, in a cohort of adult dystrophic patients (Duchenne, Becker and Limb-Girdle Muscular Dystrophy).
Methods: A prospective randomized, single centre pilot trial was conducted at University Hospital Sta.
This will be a single centre pilot randomised controlled trial.
As a single centre pilot study, few patients with limited follow-up were included.
Limitations include the small number of patients in a single centre pilot study and the radiotherapy techniques employed, which although 'state-of-the art' at the time, have now been superseded by intensity-modulated and image-guided methods.
This prospective, single centre pilot observational study was conducted over a 3-month period in daily practice patterns, to assess per-dialysis events and inter-dialysis complications that could interfere with erythropoiesis in patients undergoing hemodialysis.
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And on 11 September - investigators believe - it was Atta who led the attack on the World Trade Centre, piloting American Airlines Flight 11 into the north tower at 8.45am.
This study was designed as a prospective, non-randomized single-centre pilot study.
The radiographers' log used in a previous single-centre pilot study [14] was adapted to record displacement and correction data.
In a multi-centre pilot study, we have demonstrated a lack of confidence among UK trainee doctors in managing diabetes.
This was a single-centre pilot trial, with a short follow-up period and a high rate of attrition (particularly in the sample of relatives).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com