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In each amplicon, the precursor miRNA resides in the centre of the sequence.
We found that such transcripts generally shear near the centre of the sequence (data not shown).
The MM-sequence differs from that of the PM by a single complementary mismatch in the centre of the sequence.
The ten genes at either end and in the centre of the sequence inversion can be found listed in the supplementary materials [Additional file 1].
Intriguingly, the connecting loop in the centre of the sequence also contains lysines K107 and K108 that correspond to the Eco1-targetted lysines K112 and K113 in ScSmc3.
For example, target sites surrounding long UTR edges were associated with lower expressed protein levels than those around the centre of the sequence (15).
Similar(51)
A second approach to HIV-1 diversity derives vaccine immunogens from 'centralized' sequences, which employ consensus/average, or centre-of-the-tree[24] sequences or extrapolated aa to a common clade or group ancestor[5].
This registration is relatively minimal, in that there is a distribution of the centre of the sequences about the registry plane, with a standard deviation of ≈ 1 Å.
The empirical null distribution is approximately uniform near the centre of the protein sequence and decreases sharply near the sequence extremities.
The second gRNA sequence (5′-TTTGTAGGTGTAACATATAC-3′) was selected towards centre of the coding sequence (ATG + 539 bp).
The observation that at 80°C Tse1 cleaves within the hairpins indicates that an A A or T T mismatch at the centre of the recognition sequence (5'-GC(A/T)GC-3') does not prevent its restrictive activity.
More suggestions(16)
centers of the sequence
points of the sequence
positions of the sequence
centre of the house
centre of the département
centre of the craft
centre of the lesion
centre of the business
centre of the oblast
centre of the district
centre of the operation
centre of the target
centre of the heating
centre of the fight
centre of the state
centre of the book
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