Prepregnancy care is lacking in the region, with only 14% in peripheral sites and 65% centrally receiving it.
Within the same operating session patients were randomized centrally to receive either D1 or D2 surgery.
Participant pairs were computer-randomized centrally to receive the algorithm (group A) or no further RT-CGM interpretation guidelines (group B) for 16 weeks.
Following stratification, subjects will be randomized centrally to receive either the lactate-containing Balance solution or the bicarbonate buffered Bicavera® solution for a period of 10 months.
Eligible patients were stratified according to their PS (WHO 0 1 vs 2) and their best response to docetaxel/platinum first-line chemotherapy (CR+PR vs SD+PD); patients were randomised centrally to receive either gemcitabine (Gemzar®, Elli Lilly, Indianapolis, USA), 1000 mg m−2, as a 30-min intravenous (i.v).v
(Nursing executive, Facility 2) Both facilities supplemented the results received centrally with local data collected at more frequent intervals, including a shorter questionnaire given to all patients discharged from the facility.
Phase I: Five centres received centrally prepared PBMCs from 3 HLA-A2+ donors, peptides (Peptide Synthetics Peptide Protein Research Ltd., Bishops Waltham, UK). and multimers (kindly supplied by the Department of Immunology, Institute for Cell Biology, Eberhard-Karls University Tübingen) sufficient to perform the requested assays.
Phase II: Six centres received centrally prepared PBMCs from 2 HLA-A2+ donors, peptides (Peptide Synthetics Peptide Protein Research Ltd), multimers (production in-house), X-Vivo 15 medium (Lonza Group Ltd., Basel, Switzerland), l-glutamine (PAA Laboratories Ltd., Yeovil, UK ., Pen/Strep (PAA), human AB serum (Lonza Group Ltd).
We also observe that the receiving antennas that are lying centrally have the smallest position estimation errors.
SSA's CDR Waterfall file contains information on centrally initiated FMRs which received a DDS determination.
