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In AVAiL, 4/10 (40.0%) patients with severe PH had tumours described as central, although tumour centrality was not defined prospectively in the protocol [ 5].
This greater degree centrality was not driven by single connections but by greater connectivity between the caudate and numerous brain regions.
While the change in degree centrality was not correlated with our measures of the visual properties of the environment, we nonetheless examined whether activity in the posterior hippocampus was selectively correlated with the change in degree centrality when accounting for the other measures of the visual properties of the environment.
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Nodes with the same degree centrality are not necessarily equally central as this will depend on how their contacts are connected.
That centrality is not just geographic.
Third, we show that the degree of interaction between these core regions and the rest of the brain varies over time, indicating that their centrality is not stationary.
Thus, the right posterior hippocampal response to the change in degree centrality is not explained either by other properties of the environment and appears to track the change in degree centrality.
Thus, the right posterior hippocampal response to the change degree centrality is not simply explained either by changes in distance to the goal or by visual properties of the environment.
Furthermore, centrality is not reduced to one person or one sector.
Findings support the idea that EC mediates the interaction between them, for centrality is not due to trauma.
As we are going to perform a social network analysis of the coauthorship time slices – and some measures (like eigenvector centrality) are not well-defined for unconnected graphs – we limit our following analysis on the largest connected component.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com