Third, a set of citation and usage degree centrality measures such as Out-Degree Centrality, In-Degree Centrality and Undirected Degree Centrality.
In this light, greater degrees and centralities of cancer genes in comparison to non-cancer genes within the interactome have been observed (Jonsson and Bates, 2006; Wachi et al., 2005).
We evaluated the centrality measures of complex disease genes in comparison with essential and monogenic disease genes in the human interactome.
This suggests that there are stronger rank correlations between different centrality indices in the random networks, in comparison to the results obtained from the HD, HO and total networks.
The experimental results show that the integration of network topology and gene expression increased the predictability of essential proteins in comparison with those centrality measures only based on network topological features.
With the integration of network topology and gene expression, the same group of researchers proposes a new method called PeC [ 23]which increases the predictability of essential proteins in comparison with those centrality measures only based on network topological features.
We measure the performance of the method in comparison with established alternatives, such as ensemble non-centrality, on example models of different complexity.
In comparison, the Spearman rank-order correlation between the JIF and Citation Betweenness Centrality is only 0.52.
For each centrality metric comparison, we used the highest ranking individual for that particular metric, e.g. to compare which rules are the best for generating high P-centrality, we used the highest ranking P-centrality individual from each network.
Given the directionality of edges, retweeting activity is measured by node in-strength centrality (weighted in-degree) and influence by out-strength centrality (weighted out-degree).
