The chanting of Tibetan monks generally consists of deviations around a central tone, with bells and brass creating an ambient halo.
This work, an evocation of breath rhythms and rippling waves, included considerably more than one note but pulsed and throbbed around a central tone all the same.
Individual tone frequencies were separated by three-semitone steps with the central tone set at 225, 900, or 3600 Hz (low, medium, or high frequency) in different blocks.
The unique chill of Fassbinder's direction of actors, with its contained and formalized passions, remains one of the central tones of modern cinema.
Many shamanic songs employ only one or two central tones, while other genres from this region feature four-, five-, or six-tone scales, some with intervals of unequal sizes.
Derived from dolus, a vernacular-Latin noun meaning "suffering," dor indicates, according to the classicist Anca Vasiliu, something more particular and estranged than melancholy, less sentimental and self-indulgent than Weltschmerz — and, it occurs to a reader, strikes the central emotional tone of both the French-Romanian aphorist Emil Cioran and the Romanian-American artist Saul Steinberg.
Hence, it can be deduced that β-glucan possesses potential to enhance central cholinergic tone via inhibiting AChE enzyme.
Several previous studies revealed that vasoconstriction of RCVS was associated with sympathetic over-activity based on clinical observations or hypotheses including central vascular tone changes, aberrant sympathetic response, pheochromocytoma, and autonomic dysreflexia [7 10].
This study was designed to determine if increasing central noradrenergic tone using atipamezole, an alpha-2 adrenoceptor antagonist, could induce a long-term improvement in motor performance in rats subjected to ischemic brain damage caused by permanent middle cerebral artery occlusion.
The proposed pathophysiology of RCVS has been linked to sympathetic overactivity based on clinical observations or hypotheses including central vascular tone changes [8, 24], aberrant sympathetic response [10], blood pressure surge [5], triggers [3, 5], sympathomimetic agents [3, 12, 13], pheochromocytoma and hypertensive crises [25], and autonomic dysreflexia [26], etc.
Moxonidine, for example, is thought to attenuate central sympathetic tone either by stimulating central I1-imidazoline receptors in the medulla oblongata [4], [5], [6], or via central presynaptic alpha-adrenoceptors [7], thereby reducing sympathetic tone in the central nervous system.
