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Protein-protein interactions (PPIs) are central to the proper functioning of the most basic molecular mechanisms underlying cellular life, and are often perturbed in disease states.
Here, we examined the underlying mechanism that leads to these distinct biological responses that are central to the proper functioning of the adaptive immune system.
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Hence, lectins have sufficient properties to affect the leptin system indirectly, through effects on metabolism central to the proper function of the leptin system, and possibly also directly through interaction with leptin or the leptin receptor.
Cereal lectins could thus cause leptin resistance either indirectly, through effects on metabolism central to the proper functions of the leptin system, and/or directly, through binding to human leptin or leptin receptor, thereby affecting the function.
We further propose lectins as a cereal constituent with sufficient properties to cause leptin resistance, either through effects on metabolism central to the proper functions of the leptin system, and/or directly through binding to human leptin or human leptin receptor, thereby affecting the function.
It's hard to overstate the importance of structure to the proper functioning of a biological system.
Easy access to credit is essential to the proper functioning of many high-income economies.
These legal obligations are essential to the proper functioning of universities and were restated in the recent Higher Education and Research Act.
One that is deemed vital to the proper functioning of any open democracy, including Egypt's with its new constitution.
Their ability to do so quickly is vital to the proper functioning of those heart cells.
Public participation and information is essential to the proper functioning of a democracy.
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