With central adjudication, our specificity was likely close to 100%.
Here we seek to identify TFs that act cooperatively to define CNS (central nervous system) specificity of an enhancer.
When we focus on one particular decision threshold, the changes in sensitivity and specificity are central.
Addition of the central loop scores increased specificity, decreased false positive rates, and reached Youden Index 1.
A number of research groups have undertaken imaging of NPSLE, with hope of providing much needed specificity of central nervous system involvement within SLE.
Overall, these behavioral studies further demonstrated the specificity of central effects elicited by tat-cyclotraxin-B after intravenous injections and confirmed its pharmacological potential in vivo, for its use in animal models of brain disorders.
A central question is how specificity in cellular responses to the eukaryotic second messenger Ca2+ is achieved.
*MIRU, mycobacterial interspersed repetitive unit; Se, sensitivity; Sp, specificity; CAS, Central Asian; EAI, East African–Indian; MAF, M. africanum; MBOV, M. bovis; LAM, Latin American.
GFAP was chosen because of its high specificity for central nervous system astrocytes and its strong association with GCS, injury severity, intracranial pathology and outcome after TBI [ 7, 8].
The geographic specificities of Central Yakutia, favorable to the development of a pastoralist economy and reflecting the environmental conditions of the South, certainly initiated the development of the Yakut culture in this region.
