Sentence examples for central resistance from inspiring English sources

The central resistance model states that central hypothalamic pathways are defective (resistant to leptin and others such as insulin).

To assess whether adding liothyronine (LT3) to levothyroxine (LT4) monotherapy normalizes serum thyrotropin (TSH) and thyroxine (T4) concentrations in children with congenital hypothyroidism and central resistance to thyroid hormone.

The cumulative new knowledge favors a unified central leptin insufficiency syndrome over the, in vogue, central resistance hypothesis to explain the global adverse impact of deficient leptin signaling in the brain.

The pathogenesis of obesity is characterized by hypothalamic inflammation and subsequent central resistance to leptin.

Impaired leptin transport, especially coupled with central resistance, results in obesity.

This defect in leptin action in obese individuals suggests that human obesity may be associated with central resistance to leptin [ 15].

Rifampicin-resistance mutations were identified by sequencing the central resistance-determining region of rpoB as described previously [ 24]; streptomycin-resistance mutations were identified by sequencing part of rpsL using primers fwd 5'-ATGATG GCGGGandGTTG-3' and rev 5'-CTTCCAGTTCAGATTTACC-3' [ 5].

In this review, we discuss the novel concept of obesity-induced central ghrelin resistance in neural circuits regulating behavior, and impaired ghrelin secretion from the stomach.

This is not surprising given that FVC diminishes only in the event of air trapping, which is generally due to peripheral airway obstruction and not to increased central airway resistance due, for instance, to a tracheal tube.

Adiposity signaling and biological defense against weight gain: absence of protection or central hormone resistance?

The development of central leptin resistance in C57Bl/6J mice requires exposure to a high-fat diet for 20 weeks[14], [14].