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The central regulator which controls the expression of LEE genes is Ler, a 15 kDa protein encoded by the first gene of the LEE1 operon, which is a HNS-like regulatory protein [ 11, 13, 26– 29].
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Our previous studies showed that C. neoformans Cwc1 and Cwc2 are two central regulators which coordinately mediate blue light-inhibited sexual filamentation [32], [33].
Taken together, these data suggest that ZEB2 is a central transcriptional regulator, which controls gene expression necessary for the progression of metastatic cancer.
The protein kinase A (PKA) activates among others the central regulator Prf1 which is responsible for expression of a large set of genes including the a and b mating type genes.
Although microRNAs (miRNAs) are central epigenetic regulators, which substantially affect the development and progression of cardiovascular disease (CVD), no data on miRNA dysregulation in CKD-associated CVD are available until now.
Here, the central regulator is MEF2 which corresponds to our central hub in muscle MEF2A.
A separate proposal would merge the central bank with the country's financial regulator, which could result in a de facto demotion for Mr. Simor if the new body had its own chief.
As demonstrated, hepcidin is synthesized in the liver as a central regulator of iron metabolism which regulates the iron absorption in intestine and the release of iron from macrophages [ 16, 17].
The circadian-regulated gene CONSTANS COO) is a central regulator of this pathway, which coordinates light and clock inputs in leaves to trigger the expression of florigen gene FLOWERING LOCUS T (FT) [ 2, 3].
The UK regulator, which used to be the Postgraduate Medical Education and Training Board (PMETB), repeatedly stated that reliability is of central importance in assessment [ 1- 4].
There's no central regulator like the Federal Reserve, which oversaw the American tests.
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