Sentence examples for central protein from inspiring English sources

We further propose the concept of DNA repair hubs that coordinate DNA repair pathway crosstalk to identify central protein targets that could play a role in designing future drug targets.

The central protein of the system, C3, participates in an amplification loop that can lead to rapid complement deposition on a target and, if excessive, can result in host tissue damage.

That phenotypic potential is connected with fitness effects of the single-gene knockout supports this notion; while Hsp90 is a functionally important and central protein, its direct buffering role appears an exception rather than the rule of phenotypic capacitors.

Although monocytes clearly are capable of synthesizing the central protein of the complement cascade in response to inflammation, this ability does not appear to have an important role in vivo.

In kidney, TRPC6 is enriched in the podocyte foot processes and in collecting ducts, it was also found to be associated with nephrin and podocin [10], both central protein components of the slit diaphragm.

VeA as the central protein is N-terminally associated with VelB and C-terminally with LaeA.

Specifically, we first included the neighboring proteins that are 1 hop from the central protein.

Step seven: Validation of the backbone network and the NOS3 as central protein.

TARDPB (TDP-43) appears to be a central protein in our autophagy-related sub-network.

Apolipoprotein B is the central protein of very-low-density lipoprotein, intermediate density lipoprotein, and LDL.

C3 is a central protein involved in the classical pathway of complement activation [ 46].