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The clinical signs in the dog are erythematous nodular lesions of varying dimensions with a central pore from which there is a bloody discharge; the end of the parasite is visible through the pore.
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The diamond-shaped markings on their upper surfaces, signs of interior air chambers, have a central pore through which air diffuses.
The central pore region, which conducts the ions, is formed by the association of the C-terminal S5 and S6 helices and the intervening "P-loop" from each of the four domains in a pseudosymmetric arrangement.
Even when considering symmetry-related molecules in the P32 crystal lattice, the resulting arrangement does not reveal a central pore with which AidB could sequester DNA.
Spastin forms a ring-shape hexamer containing a prominent central pore into which the C-terminal tail of tubulin is attached and pulled.
This helix sits above the central ssDNA binding channel and forms a part of the central pore through which the translocating strand exits the helicase motor domains as the helicase translocates in the 5′ direction.
Previously, researchers had identified several genes that are required for the formation of the uniporter, but it had not been established which of these encodes the central pore through which the calcium ions pass.
Class averages revealed increased definition of the central pore, which displayed diameters of 1.9 and 2.6 nm for the putative pentamer and hexamer forms, respectively.
Single-particle three-dimensional reconstruction revealed that MG23 forms a large bowl-shaped complex equipped with a putative central pore, which is considered an assembly of the small asymmetric subunit.
It acts as a signal that is recognized by the translocon channel, a bipartite complex with central pores through which precursors penetrate into the plastid stroma [ 13, 14].
Six connexins form a hexamer around a central pore called a connexon, which is trafficked to the extracellular membrane (Evans and Martin, 2002).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com