Once it reaches the central nervous system it causes inflammation leading to fever, pain, partial paralysis, difficulty swallowing, hallucinations, and paranoia.
As this activity is also found in bladders that are isolated from the central nervous system, it seems that it is generated within the bladder wall.
Although the centralized nature of the pain implies that it originates in, or is amplified by, the central nervous system, it does not rule out peripheral nociceptor input as a contributing factor to the pain.
The pygidial commissure could be a remnant of segmental ganglia but, in the absence of a pygidial central nervous system, it cannot carry the axons of centrally located interneurons as annelid segmental commissures normally do.
To explore the role of proton trafficking in the central nervous system, it is important to complement physiological studies with its molecular counterpart.
In the central nervous system, it modulates attention, behavior, motor tone, temperature and pain.
While CGRP is expressed abundantly in the central nervous system, it also plays an important role in the peripheral nervous system.
Although there's no particular reason this tech wouldn't work in the central nervous system, it would have to be smaller and testing would be much more complicated.
The new British law defines a substance as psychoactive if "by stimulating or depressing the person's central nervous system, it affects the person's mental functioning or emotional state".
Therefore, once the infectious agent reaches the central nervous system, it may spread centrifugally from the brain to the salivary glands through the autonomic nervous system.
