"Any time you have a problem mortgage, the transfer tax is a central issue of the discussion," said Benjamin F. Needell, a partner at the law firm Skadden, Arps, Slate, Meagher & Flom.
The central issue of yesterday's discussion was the disclosure, after the death of Jesse Gelsinger, a patient in a gene expeirment at the University of Pennsylvania, that scientists had often failed to inform federal agencies of "serious adverse effects" involving patients.
That was the central issue of dispute in two discussions that sprang up this month on online message forums Reddit and ResearchGate.
Although issues of wages, benefits and working conditions are also under discussion, the future of organized labor in fast-growing areas like high-speed lines and wireless communications has emerged as the central issue of this strike.
This is a central issue in any discussion of barefoot-style running, because one of the supposed hallmarks of running shoeless or in minimalist footwear is that doing so promotes a forefoot landing.
The central issue, then, under discussion today was whether the site had been used with permission or not.
As a result of such variations, the Eucharist has been a central issue in the discussions and deliberations of the ecumenical movement.
The host country proposes a central issue for the discussions in which the Heads of State and Government participate.
That central issue animated much of the discussion at an unusual gathering earlier this month at a lodge north of San Francisco.
A questioning of the relation between science and technology was the central issue in one of the earliest discussions among analytic philosophers of technology.
