To assess interobserver reliability between 2 central readers of cranial ultrasound scanning (CUS) and accuracy of local, compared with central, interpretations.
Of course, there have been calls for alternatives or interactionist models where heredity and development, epigenesist and preformation, work together, but these have often been offered as alternatives than as central interpretations.
If films are digitized at each site and transmitted electronically to a central reading site, all interpretation can be done by a designated panel of TB radiology experts with an increase in the accuracy of diagnosing active and inactive PTB.
For large studies covering geographically scattered participants, self-reported data are paramount, and examinations of the validity of these data are central to interpretation of the results.
Results: Of the central histologic interpretations, 26 of 288 interpretations (9%) differed from local results, 97 of 246 cytologic/histologic pairs (39%) were discordant, and 21 subjects had progression to high-grade squamous intraepithelial lesions by histologic evidence.
This concept has been central to interpretations as diverse as the formation and evolution of the landscape and the development of geochemical exploration models.
For all this, however, a surprising number of legal theorists agree at least at an abstract level about one central characteristic of interpretation, namely that interpretation is a Janus-faced concept, encompassing both a backward-looking conserving component, and a forward-looking creative one.
Such analysis was the domain of the field of computational biology, in which computational methods and modeling are central to the interpretation of data on biological systems.
