Thus, the VMH AMPK-SNS-BAT axis appears to act as a canonical central mechanism integrating central and peripheral regulation of energy stores.
The p300/CREB-binding protein is a central integrating coactivator [6], which, in a hypoxia-dependent manner, owing to its binding the CAD of HIF-1α or HIF-2α, enables the recruitment of various accessory cofactors, such as the steroid receptor coactivator, transcription intermediary factor-2, or redox factor Ref-1 [4,6].
Typically, data must go through a process called ETL (Extract, Transform, Load) [3] where they are extracted from their sources, cleaned, transformed, and mapped to a common data model before they are loaded into a central repository, integrated with other data, and made available for analysis.
Data were retrieved from central registers integrated in the Longitudinal Database for health insurance and labour market studies (LISA).
Cell migration is a central, highly integrated multistep process required for maintenance and development of numerous physiological processes.
A central application integrated into this health informatics tool was an application for asynchronous, written dialogue between the users according to the findings in the survey of the literature.
Nonetheless, we identified interaction hub enzymes that are located at central positions integrating several metabolic systems and whose removal would severely impact the structural integrity of larger portions of the metabolism-focused metabolic network (fPIN, Table 4, Figure 7A, B).
Finally, the central unit integrates the data collected by the fleet in order to generate updated traffic status maps.
LuxO is the central regulator integrating the quorum sensing signals controlling autoinduction of luminescence in Vibrio harveyi.
The yeast Sac3 Cdc31 Sus1 Thp1 (TREX-2) complex facilitates the repositioning and association of actively transcribing genes with nuclear pores (NPCs)—"gene gating"—that is central to integrating transcription, processing, and mRNA nuclear export.
The software creates an integrated electronic medical records system that aims to link every department in a healthcare facility to a central database, integrating the process so that everyone from the receptionist to the doctor to the lab to the pharmacy can track a patient's progress.
