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Sensitivity analyses on central input parameters have been performed.
These results were robust to changes of central input parameters and robust to potential further price decreases of docetaxel.
These results were robust to changes of central input parameters and robust to further potential price decreases for docetaxel.
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The key input parameters used throughout our VTOL physics-based model are defined in Table 1.
Table 1 summarizes the key input parameters in the model.
Another key input parameter is the in vivo relevant solubility.
A key input parameter to the model is TB incidence.
If the central tendency estimates of the input parameters (i.e., means, medians) in this analysis are inaccurate, they could bias the estimates of the central tendency and percentiles of the model output even if the variability in the output distribution is accurately estimated.
Key MPPD model input parameters.
In the context of this analysis, this includes both the uncertainty in estimating the true values of the central tendency and percentiles of the input parameters, and to the uncertainty in specifying their correct distributional form.
The minimum and maximum changes reflect the outcomes where the central tendencies of each of the input parameters are simultaneously altered in the direction that produces the greatest change in the output.
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