Sentence examples for central impact on from inspiring English sources

Many of these disruptions can often be considered side products of a disease that have no significant functional consequence, but others can frequently play a major causal role in disease and have a central impact on the initiation or progression of a pathology.

The distinct difference observed in pathogen susceptibility resulting from the different inoculation methods indicated that the stomatal phenotype of max2 plants has a central impact on the outcome of the infection i.e. more open stomata of max2 mutant plants increase bacterial entry to the apoplast of these plants.

Moreover, the high strains induced by the lateral impact were mainly focused on the ipsilateral side of the brain, while those induced by the central impact were more diffusely located on both sides.

Our findings provide the first direct insight into its central neural impact on the developing human brain.

Within the ante- and perinatal factors, genetic susceptibility, the immaturity of the surfactant homeostasis, intrauterine and perinatal infections, and lung growth restriction due to placenta insufficiency are central factors impacting on the development of BPD.

As might be expected, artificially restricting information outside central vision impacted on the sensitivity of the face system and its performance, as the greater ability humans have in recognizing same- compared to other-race faces was abolished (e.g. [24], [39], [40], [41], [42]).

The latter is now accepted as a central player, impacting on most of the mechanisms underlying gastroesophageal reflux (low LOS sphincter pressure, TLOSRs, oesophageal clearance, and acid pocket position), explaining its association with more severe disease and mucosal damage.

Since the sample of the ten interview subjects was in accordance with the strategic sample concerning the most central variables impacting on quality of life, the generalizability of the interview study could be evaluated as relatively good.

The latter is now accepted as a central player, impacting on most mechanisms underlying gastroesophageal reflux (low sphincter pressure, transient lower oesophageal sphincter relaxation, oesophageal clearance and acid pocket position), explaining its association with more severe disease and mucosal damage.

There is also the freshness of its central premise: the impact on an American family when a 70-year-old retired professor begins transgender reassignment.

Given the ease of this novel approach, it should be possible in the future, to test many known genetic mutations or well defined inhibitors, e.g. of signaling pathways or key enzyme systems, for their impact on central PMN functions.