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Exact(4)
Let's look at the central entries.
Let's look at those long, central entries closely.
We take the IFT so as to obtain the vector ṽ = F − 1 Ṽ representing the result of the extrapolation procedure whose M central entries coincide with ( overline{mathbf{v}} ). .
When anxiety-related behavior was analyzed, neither young nor adult Syn KO mice significantly differed from control mice in the number of central entries (Fig. 1B).
Similar(56)
Let's look at the central entry, "December 31".
Your hint is at the central entry 66 Across, IT'S RAINING CATS AND DOGS.
The only entries from your initial grid that survived our edits were your central entry and 15- and 17-Across.
I made it all the way to the central entry A TO, including the long down ROSES ARE RED.
WEDNESDAY'S PUZZLE — There's a double trick to today's puzzle, which pays off nicely at the central entry.
Its Classical symmetry — the axial geometry, the columns framing a central entry — taps into a lineage that runs back to Mies van der Rohe's 1968 Neue Nationalgalerie and Schinkel's 1828 Altes Museum in Berlin and even further, to the Parthenon.
It would have been an interesting (note that I said interesting, not nice) touch if all of the clues were FILL IN THE BLANKS, to highlight the central entry.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com