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Meanwhile, central dysfunction of dopaminergic hypothalamo-spinal (A11) neurons has been strongly implicated in the pathophysiology of RLS, and the dopaminergic hypothesis has been supported by observation of beneficial effects of dopamine receptor agonist therapy on RLS symptoms [13].
Impaired or altered 5-HT neurotransmission appears to be a central dysfunction leading to depressive and anxiety symptoms.
Under this model, weight loss in RYGB might be explained, in part, by amelioration of central dysfunction.
Our findings point to a central dysfunction of respiratory regulation in transgenic mice in comparison to wild-type littermate mice.
Fine matrix mapping suggests that the abnormal accumulation of lipofuscin in cases of cone-rod dystrophy represents a transitional stage between relatively preserved parafoveal function and severe central dysfunction that is likely to precede central atrophy [ 26, 27].
Abnormalities of the spinal cord, anterior horn cells, and peripheral nerves are not part of the usual clinical spectrum of myositis, so all appear unlikely causes of central dysfunction.
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Physical therapy for central vestibular dysfunction.
Central noradrenergic dysfunction with autonomic nervous system dysregulation are reported in major depressive disorder (MDD).
Mentis, PhD, Pathology & Cell Biology, will receive $2,229,605 over five years from the National Institute of Neurological Disorders and Stroke for "Mechanisms of Central Synaptic Dysfunction in SMA" in a competitive renewal.
To describe a patient with clinically documented autosomal dominant vitreoretinochoroidopathy who has had 11 years of progression from initial description and now demonstrates evidence of central cone dysfunction.
These observations suggest that age-related central auditory dysfunction and its corresponding pathological changes are present in both naturally aging rats and the d-gal mimetic aging model.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com