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For multi-center studies, this information may be gathered by personnel at individual sites or by staff at a central coordinating center.
Similarly, data were monitored, verified, and analyzed by a highly-qualified, central coordinating center (INSERM CIE 1).
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The randomization scheme will be coordinated through the central data coordinating center (DCC) and the randomization is stratified by each participating site.
Subjects will be enrolled at seven clinical centers across the United States and data will be analyzed by the central data coordinating center.
Side effects and adverse events are tracked by computer at the central data coordinating center and unblinded data are reviewed by an independent safety monitoring board.
We believe that the insights and experiences that we have described in this paper should be helpful to other research consortia undertaking projects that generate enormous datasets and that must transfer those data expeditiously from field sites (including some very rural sites) in multiple developing countries to a central data coordinating center.
The repository, central database and coordinating center is located at Peking University First Hospital, Beijing.
A centralized data coordinating center supervises data collection and analysis.
The local team leader and the project manager of the coordinating center (central project manager) compare the original English to the back-translation and either approve or question each item in the back-translation.
TrialNet, an offshoot of the DPT-1 study group, is composed of 18 clinical centers and 170 affiliates across nine countries, a coordinating center, and a central core laboratory.
They were later transported to the coordinating center in Dijon Francee) and then sent to the central biological laboratories (Inserm UMR 866, Dijon, France) or stored at −80°C according to French rules (cryopreservation in the Center of Biological Resources Ferdinand Cabanne of the Dijon University Hospital, France).
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