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As the central controllers of programmed cell death, caspases initiate the transduction of apoptotic signals by activation of members of the TNF superfamily and their DEATH receptor28, which can eventually result in the release of lysozymes to digest the symbionts29.
SC are central controllers of early testicular differentiation, male sexual development, and germ cell differentiation in adult life.
Multidomain protein kinases, central controllers of signal transduction, use regulatory domains to modulate catalytic activity in a complex cellular environment.
Whatever the case might be in cancer and stem cells, in mostly normal human cell lines (in particular HEK293 and MCF10A cells) LATS1/2 function downstream of G-protein-coupled receptors (GPCRs) as central controllers of YAP/TAZ activities [ 2].
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The central controller of the distribution grid obtains the distribution network status information and exchanges control and status information with the central controller of the VPP.
Aramburu, J., Heitman, J. & Crabtree, G.R. Calcineurin: a central controller of signalling in eukaryotes.
The Target of Rapamycin Complex is a central controller of cell growth and differentiation in eukaryotes.
The target of rapamycin (TOR) is a large (281 kDa) conserved Ser/Thr protein kinase that functions as a central controller of cell growth.
The mTOR is a member of serine/threonine protein kinase family that functions as a central controller of growth, proliferation, metabolism and angiogenesis, but its signaling is dysregulated in various human diseases especially in certain solid tumors including the glioblastoma.
The central controller of the network called PAN coordinator can optionally bound its channel time by using a superframe structure (i.e., beacon-enabled PAN).
A forecaster located at the central controller of the PEESS can calculate the temperature change rates ( Updelta tau_{i}^{text{on}} (t) ) and ( Updelta tau_{i}^{text{off}} (t) ) for each cell to predict its operating status based on (3).
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