Nevertheless, given the central role of constitutive IP3/Ca2+ signaling in regulating mitochondrial bio-energetics, IP3R2 upregulation may enhance mitochondrial function and energy production to accommodate for the higher metabolic activity and the induced proliferation of cancer cells.
Following the work of Lorraine Daston and Kay Milton on moral economies and ecologies of emotion, respectively, this article takes these studies as its central concern, showing the constitutive role of emotion in the generation of environmental knowledge.
Plant secondary metabolites play a central role in the constitutive and induced chemical defence against herbivores.
Nrf2, a member of the bZIP family of transcription factors, is a central regulator of both constitutive and inducible ARE-related gene expression (Itoh et al. 2004).
Caspase-3 represents a central element in neutrophil constitutive apoptosis as its activation induces the characteristic changes in the apoptotic cell, including the final DNA fragmentation [ 31].
Further, transcription factor Nrf2, a member of the Cap 'n' Collar family of bZIP proteins, is a central regulator in both constitutive and inducible ARE-controlled gene expression and innate immune response.
Experiments with rotary shear devices illuminate constitutive behavior there, central to the dynamics of fast-moving glaciers, and provide a foundation for interpreting the sedimentary record of glacier slip and associated sediment transport.
This defect in DSB repair reflects a constitutive sequestration of the central HR protein, Rad52, at telomeres, and a decrease in its recruitment to DSBs, suggesting that telomerase exerts an indirect effect on global genome stability.
We recently demonstrated that high constitutive NOXA levels are central for hypersensitivity of embryonal carcinoma cells to cisplatin.
With the presence of swastika tattoos, and the general demography of the rally's participants, it is obvious that race still remains central to our political culture in a constitutive sense; being "white" continues to play a formative role in how we construct what it means to be authentically Aussie.
