Our research question was centered on "which" factors were a priority.
Transcription regulation analysis using GeneGo's MetaCore generates sub-networks centered on transcription factors using the 17 genes discovered by Backward Chaining Rule Induction.
A supplementary package, pathprintTF, is also provided, containing a similar framework and database to pathprint but built upon protein interaction modules centered on transcription factors rather than pathways to enable cross-platform comparison of transcriptional control elements.
Only since the 1970s, and, as Berridge shows, partly in response to the debates over smoking and health, has this new agenda centered on risk factors and individual lifestyle choices come to dominate public health debates in Britain.
Embryonic stem cell (ESC) pluripotency is governed by a gene regulatory network centered on the transcription factors Oct4 and Nanog.
Published: October 4, 2012 Self-renewal of mouse embryonic stem cells (ESCs) is under the intrinsic control of a gene regulatory network centered on the transcription factors Oct4, Sox2, and Nanog (Chen et al., 2008; Kim et al., 2008; Loh et al., 2006) (reviewed in Chambers and Tomlinson, 2009; Jaenisch and Young, 2008).
A gene network centered on hepatic nuclear factor and GATA6 was identified in AC, suggesting a role in glandular cell differentiation of the cervix.
Furthermore, in AC a network of genes centered on HNF transcription factors (HNF1B, HNF4A and HNF4G) and GATA6 was also identified.
No priors were used for the purpose of experimental design, and the hypotheses were centered on identifying which factors were deemed valuable and whether differences in priorities could be identified across stakeholders or countries.
Most of the descriptions of these imbalances have centered on abnormalities of tissue factor, factor Xa, thrombin, or proteinase-activated receptors.
