Sentence examples for cellular transformations that from inspiring English sources

Gaining a full understanding of the mechanisms of action of natural products as therapeutic agents includes observing the effects of natural products on cellular morphology, because abnormal cellular morphology is an important aspect of cellular transformations that occur as part of disease states.

The hypothesis highlights the importance of social exploitation in cell evolution and how a social environment can buffer drastic cellular transformations that would be lethal for planktonic forms.

The hypothesis also emphasizes how a social environment can buffer drastic cellular transformations that would be lethal for single-celled forms.

Remodeling of energy metabolism is a recognized hallmark of cellular transformation that supports the sustained proliferation of cancer cells under conditions that restrict normal cell growth.

However, the underlying molecular mechanisms contributing to the complex immunological cellular transformation that is associated with the progression of anti-NMDAR encephalitis remain to be adequately explored.

The homodimerization of HER2 is primarily detectable in case of cellular transformation that leads to HER2 overexpression, particularly in case of BC where HER2 gene was found amplified in 20% of cases up to 25 50 copies.

Our finding that normal OSE cells, unlike cell lines derived from ovarian tumours, abundantly express 11 βHSD-1 mRNA but are essentially devoid of 11 βHSD-2 mRNA, supports the concept that the pattern of 11 βHSD isoform expression is a defining feature of neoplastic cellular transformation that could have particular relevance to the ovary.

Collectively, these data suggest that cellular transformation that results due to deregulation of cyclin D1a is a latent event.

However, in cancer cells such requirement is modulated by the degree of cellular transformation, so that neoplastic or transformed cells continue proliferating in Ca2+-deficient media [ 8].

Previous studies have reported that overexpression of Nck1 in fibroblasts induces cellular transformation and that these cells form tumors in mice [ 16, 17].

Recent work indicates that DDX3 can participate in the transcriptional regulation of a diverse set of genes involved in apoptosis and cellular transformation in ways that impact cancer progression [17].